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Andarine (S4)

What is Andarine (S4)?

Andarine is a selective androgen receptor modulator (SARM) originally developed to treat muscle wasting diseases and osteoporosis. It has shown promise in preliminary animal studies where it effectively increased bone density, muscle mass, and strength. It is currently undergoing human clinical trials.

SARMs are drugs that bind to the androgen receptor (AR), but are selective in their actions. This prevents them from causing unwanted side effects such as hair loss, gynecomastia or water retention. Moreover, Andarine is regarded as having high oral bioavailability and great muscle building properties. Phase one human trials with this drug have reportedly been successful but no studies have been published.

Andarine Benefits

Andarine is a very versatile and you can use it for cutting, recomposition or bulking.

Cutting

Andarine has similar properties to “cutting” steroids such as Winstrol and Anavar. By binding to the androgen receptor, Andarine increases fat oxidation. It also decreases lipoprotein lipase (LPL), an enzyme that causes lipid accumulation.  This sarm S4 is often compared to Winstrol since it increases vascularity and promotes a very nice “quality” hard look to the user’s muscles with no water retention.

Another great benefit to including Andarine in a cutting protocol is that it’ll prevent the loss of muscle mass while in a calorie deficit. One of the most disheartening outcomes of cutting is the loss of hard earned muscle mass. As S4 has both anabolic and androgenic effects in muscle tissue, it will not only help with fat loss, but maintain and even increase muscle mass when cutting.

Andarine also doesn’t cause the painful lower back and calf pumps associated with other popular steroids/prohormones.

Recomposition

Recomping is when you lose fat and gain muscle at the same time. In fact, this is what the majority of users are looking for. Andarine is a favorite when recomping due to its nutrient partitioning effects. One of the most common SARMS cycles is the SARMS triple stack which is a combination of Ostarine (MK2866), Andarine (S4) and Cardarine (GW501516).

Bulking

Due to its androgenicity in muscle tissue, Andarine will promote increases in strength without bloat or water retention. The weight gain from S4 may not be that great in comparison to bulking steroids such as deca or Superdrol, but the lean mass and strength gained during the cycle is kept and not lost after the cycle.

sarm s4 benefits

Pharmacologic activity of Andarine on Muscle Growth & Prostate Size

Side effects, dosages and half life

SARMs have fewer side effects than anabolic steroids because of their selectivity. Side effects such as male breast enlargement, elevated blood pressure, hair loss, acne, or the appearance of masculine traits in women (these can be observed in people who use anabolic steroids) are impossible from SARMS. Also, SARMS are not liver toxic and do not affect cholesterol levels, blood pressure, your kidneys or your prostate.

However, users may experience a suppression in luteinizing hormone (LH) and follicle stimulating hormones (FSH) from Andarine usage. LH and FSH promote the production of reproductive hormones in men and women, and suppression could suppress normal estrogen/testosterone levels. However, it is unknown if and how much S-4 would actually suppress testosterone/estrogen production in humans. It suppressed LH and FSH in castrated rats but had no effect in normal male rats.

andarine for saleBesides suppression, the most frequent user-reported side effects are visual issues such as seeing a yellow tint and difficulty adjusting to night vision. The S-4 molecule binds to the retina in the eye which causes a yellow tint to be seen. This generally occurs at night, especially when switching from a dark to lightened area. However, the side effect is not serious and will disappear immediately after the drug’s usage has been discontinued.

Buy Andarine

The recommended dosage of Andarine for men is 50 milligrams (mg) per day for 8- 12 weeks. However, women should use half that dosage. The half-life of S4 is only 4 hours so users should split up their daily dosage into and AM and PM dosage. In fact, it does not matter if you take S4 on an empty stomach or with food. Also, since Andarine is not a stimulant, taking it near bedtime will not affect sleep.

How To Use

Cutting Cycle

Week Andarine

(S4)

Cardarine (GW501516) HCGenerate ES
1 50mg/day (25mg AM 25mg PM) 20mg/day
2 50mg/day (25mg AM 25mg PM) 20mg/day
3 50mg/day (25mg AM 25mg PM) 20mg/day
4 50mg/day (25mg AM 25mg PM) 20mg/day
5 50mg/day (25mg AM 25mg PM) 20mg/day
6 50mg/day (25mg AM 25mg PM) 20mg/day
7 50mg/day (25mg AM 25mg PM) 20mg/day
8 50mg/day (25mg AM 25mg PM) 20mg/day
9 5 tablets/day
10 5 tablets/day
11 5 tablets/day
12 5 tablets/day

Recomposition Cycle

Week Andarine

(S4)

Cardarine (GW501516) Ostarine (MK2866) HCGenerate ES Clomid
1 50mg/day (25mg AM 25mg PM) 20mg/day 25mg/day
2 50mg/day (25mg AM 25mg PM) 20mg/day 25mg/day
3 50mg/day (25mg AM 25mg PM) 20mg/day 25mg/day
4 50mg/day (25mg AM 25mg PM) 20mg/day 25mg/day
5 50mg/day (25mg AM 25mg PM) 20mg/day 25mg/day
6 50mg/day (25mg AM 25mg PM) 20mg/day 25mg/day
7 50mg/day (25mg AM 25mg PM) 20mg/day 25mg/day
8 50mg/day (25mg AM 25mg PM) 20mg/day 25mg/day
9 5 tablets/day 25mg/day
10 5 tablets/day 25mg/day
11 5 tablets/day 25mg/day
12 5 tablets/day 25mg/day

 Bulking Cycle

Week Andarine

(S4)

Ligandrol (LGD4033) HCGenerate ES Clomid
1 50mg/day (25mg AM 25mg PM) 10mg/day
2 50mg/day (25mg AM 25mg PM) 10mg/day
3 50mg/day (25mg AM 25mg PM) 10mg/day
4 50mg/day (25mg AM 25mg PM) 10mg/day
5 50mg/day (25mg AM 25mg PM) 10mg/day
6 50mg/day (25mg AM 25mg PM) 10mg/day
7 50mg/day (25mg AM 25mg PM) 10mg/day
8 50mg/day (25mg AM 25mg PM) 10mg/day
9 5 tablets/day 25mg/day
10 5 tablets/day 25mg/day
11 5 tablets/day 25mg/day
12 5 tablets/day 25mg/day

 

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