Cardarine (GW-501516)

Bodybuilders and athletes have always looked forward to trying different health supplements that are available in the market. Out of the many health supplements, Cardarine or GW-501516 has been favorite among the health enthusiasts. It has been popular because of its features like fighting cardiovascular diseases and improving good blood cholesterol in the human body. Although there have been various controversies surrounding the drug, it has still gained popularity among its users. Here is a detailed review on Caradrine.

What is it?

Cardarine or GW-501516 is a promising drug developed by Glaxo Smith Kline to prevent prostate and breast tumors. The drug was manufactured in 1992 with an objective to increase HDL and reduce LDL cholesterol in the body. Later, the drug was introduced for its ability to increase acid metabolism in the bodybuilders and athletes. Its features of reducing fatty tissues and increasing endurance has made it quite popular among athletes.

How does it work?

Cardarine is a PPAR (peroxisome proliferator-activated receptor) [1]. It works similar to SARMs (selective androgen receptor modulators) with a slight difference. Cardarine targets the androgen receptors that stimulates glucose to the muscle tissues. GW-501516 is recommended as the best remedy for obesity that rapidly melts the fatty acid in the muscles. It is popularly known as the best fatty acid oxidation remedy.

Studies on Cardarine (GW-501516)

NMR analysis of serum lipoproteins from primates treated with GW501516. V ϭ vehicle, GW ϭ 3.0 mg ͞ kg GW501516.

It is also proven that Caradrine improves HDL cholesterol by 79% and simultaneously decreases the bad LDL cholesterol from the body.


Other names to denote the drug are as follows:

  • Endurobol
  • GSK 516
  • GW1516
  • GW 501516
  • GW 501,516

Benefits for bodybuilders

Cardarine or GW-501516 have numerous benefits in both medical fields and to the bodybuilders. Multiple studies reveal that Cardarine is useful for gyming activities like running and other exercises making it an exceptional medicine for the bodybuilders and athletes.

  • Enhances stamina in the body

Cardarine has been banned many times because of its potent properties. Cardarine increases stamina energy and performance in the bodybuilders due to which WADA has banned this drug. It also earned the title of “Ultimate performance enhancer” in the bodybuilding circle due to its endurance enhancing capacity.

  • Melts fats only

Cardarine in non-catabolic, thus it only reduces the amount of fat in the body. It helps lose weight without any wastage or breakdown of muscles.

  • Flexible and quick

Cardarine shows quick result when taken alone. Thus, bodybuilders who are looking for endurance increase without risking the side effects of anabolic steroids, they can give Cardarine a try.

Side effects

In the last 20 years of Cardarine use, no substantial side effects have been observed. In the beginning, people had concerns for risk in liver damage and developing cancer. However, numerous researches and studies have brought these claims to peace. The American Association of Cancer Research has also done various experiments with GW that proved the safety of the drug. In a 2008 research, GW-501516 shows good potentials in preventing the symptoms of cancer. Particularly in terms of inhibiting the growth of cancer cells in the human body.

Specific studies have also proved its reverse action on diabetes, obesity, and dyslipidemia [2]. Moreover, it can suppress testosterone and androgen side effects.

How to use GW501516

Before using Cardarine, you must note that the substantial researches have been carried on mice with near toxic doses. Despite the praises and anecdotal instances, the drug is warranted from long time use. You shouldn’t take GW more than 10mg/ml a day. However, if you are taking it for the second or third cycle, you might go for higher dosage of up to 20mg/ml a day.

The cycle length varies from person to person with a general time frame of 4 to 6 weeks. Only professional bodybuilders and athletes can take a higher dose but still, they shouldn’t go beyond 20mg/per day. You should divide the dosage into two phases: morning and evening. Intracycle or post-cycle therapy is not necessary.

What to expect after using GW-501516?

  • Boosts insulin sensitivity. The output of glucose by the liver is reduced, and the body loses fat.
  • It retains your energy level even if you are cutting on diets.
  • Improves endurance and stimulates energy in the body. It manages the flow of oxygen in the body and keeps you active.
  • Clubbed with healthy diet and macronutrients, you can get stronger muscles. It is suitable for bodybuilding and athletics.

Where to buy?

Lots of companies advertise Cardarine or GW 501516. However, you might end up buying a fake product and harm yourself. You should only buy this drug from trusted sources only.

Is Caradrine legal?

Cardarine is banned by the WADAThe legality of Cardarine highly depends on the scenarios of use. If you are a bodybuilder or an athlete, WADA has banned the intake of Cardarine due to its effects on performance. Thus, please be aware if you are a professional athlete. However, technically, GW is legal for sale as research chemicals or as medicine for treating obesity or treating cholesterol and other ailments.

Stacking Cardarine

Since there are no known side effects, bodybuilders stack Cardarine with other anabolic compounds. They combine Cardarine with individual components to make it more healthy and effective. You can stack Cardarine with almost any type of SARM. You can use it for bulking, cutting or recomping.


Cardarine is hugely popular among bodybuilders and athletes who look for enhancing endurance and getting bigger muscles. In fact, you can tremendously combat the side effects of Trenbolone with in. All in all, it helps to eliminate side effects of androgen, boost energy, build muscles while cutting fat from the body.

Although Cardarine is safe for use, the majority of researches have been carried out on mice only. Never abuse or overdose GW-501516.




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